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ASPP2 Recombinant Antibody, AbBy Fluor™ 555 Conjugated

Product Specifications

Background

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Synonyms

53BP2; ASPP2; p53BP2; PPP1R13A; Tp53bp2.

Gene ID

7159

Swiss Prot

Q13625

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

ASPP2

Clonality

Recombinant

Conjugation

AbBy Fluor™ 555

Source

KLH conjugated synthetic peptide derived from human TP53BP2

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

553nm/568nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7159

Isotype

IgG

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