VAMP8 Recombinant Antibody, APC Conjugated
Product Specifications
Background
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex.
Synonyms
VAMP8; EDB; Endobrevin; VAMP-8.
Gene ID
8673
Swiss Prot
Q9BV40
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
VAMP8
Clonality
Recombinant
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human VAMP8
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Mouse, Rat
Gene ID URL
8673
Isotype
IgG
Curated Selection
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