VAMP8 Recombinant Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex.

Synonyms

VAMP8; EDB; Endobrevin; VAMP-8.

Gene ID

8673

Swiss Prot

Q9BV40

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

VAMP8

Clonality

Recombinant

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human VAMP8

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat

Gene ID URL

8673

Isotype

IgG

Curated Selection

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