MGMT Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Synonyms

MGMT

Gene ID

4255

Swiss Prot

P16455

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

MGMT

Clonality

Recombinant

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human MGMT

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4255

Isotype

IgG

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