Caspase 14 Recombinant Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum.Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin.In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF.
Synonyms
CASP14; Caspase-14; Caspase 14; MICE; CASP-14.
Gene ID
23581
Swiss Prot
P31944
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
Caspase 14
Clonality
Recombinant
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human Caspase 14
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Mouse, Rat
Gene ID URL
23581
Isotype
IgG
Curated Selection
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