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Caspase 14 Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum.Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin.In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF.

Synonyms

CASP14; Caspase-14; Caspase 14; MICE; CASP-14.

Gene ID

23581

Swiss Prot

P31944

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

Caspase 14

Clonality

Recombinant

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human Caspase 14

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat

Gene ID URL

23581

Isotype

IgG

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