Caspase 14 Recombinant Antibody
Product Specifications
Background
Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum.Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin.In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF.
Synonyms
CASP14; Caspase-14; Caspase 14; MICE; CASP-14.
Gene ID
23581
Swiss Prot
P31944
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
Caspase 14
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Caspase 14
Applications
WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IP (1-2ug), IF (), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse, Rat
Gene ID URL
23581
Isotype
IgG
Curated Selection
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