NOTCH4 Recombinant Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system.
Synonyms
NOTC4; hNotch4; INT3; Notch homolog 4.
Gene ID
4855
Swiss Prot
Q99466
Cellular Locus
Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
NOTCH4
Clonality
Recombinant
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human Notch 4
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
4855
Isotype
IgG
Curated Selection
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