NOTCH4 Recombinant Antibody
Product Specifications
Background
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system.
Synonyms
NOTC4; hNotch4; INT3; Notch homolog 4.
Gene ID
4855
Swiss Prot
Q99466
Cellular Locus
Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
NOTCH4
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Notch 4
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
4855
Isotype
IgG
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