MST1R Recombinant Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1.
Synonyms
C met related tyrosine kinase; CD136 antigen; Macrophage stimulating 1 receptor; MSP receptor; p185 RON; PTK 8 Stem cell derived tyrosine kinase; MST1R variant RON30; MST1R variant RON62.
Gene ID
4486
Swiss Prot
Q04912
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
MST1R
Clonality
Recombinant
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human MSP receptor
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
4486
Isotype
IgG
Curated Selection
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