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FANCD2 Recombinant Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress.

Synonyms

FA D2; FA4; FAC D2; FACD 2; FACD; FACD2; FAD; FAD2; FANCD 2; FANCD; FANCD2; Fanconi anemia group D2 protein; FLJ23826; Protein FACD2; Type 4 Fanconi pancytopenia.

Gene ID

2177

Swiss Prot

Q9BXW9

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

FANCD2

Clonality

Recombinant

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human FANCD2

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2177

Isotype

IgG

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