CSF1R-IN-1
CSF1R-IN-1 is a CSF1R inhibitor with an with an IC50 of 0.5 nM.
Product Specifications
CAS Number
[2095849-04-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
C-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CSF1R-IN-1.html
Purity
98.04
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
CC1=CC=C(NC(C2=CC=CC(C(F)(F)F)=C2)=O)C=C1NC(C3=CC(C4=CN(C)N=C4)=CN=C3)=O
Molecular Formula
C25H20F3N5O2
Molecular Weight
479.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Ramachandran SA, et al. Design, synthesis and optimization of bis-amide derivatives as CSF1R inhibitors. Bioorg Med Chem Lett. 2017 May 15;27 (10) :2153-2160.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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