RAD18 Recombinant Antibody, PE-Cy7 Conjugated
Product Specifications
Background
E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.
Synonyms
E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; RAD18; RAD18, S. cerevisiae, homolog; RING finger protein 73; RNF73.
Gene ID
56852
Swiss Prot
Q9NS91
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
RAD18
Clonality
Recombinant
Conjugation
PE-Cy7
Source
KLH conjugated synthetic peptide derived from human RAD18
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
56852
Isotype
IgG
Curated Selection
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