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PRPF19 Recombinant Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex

Synonyms

NMP200; nuclear matrix protein 200; pre-mRNA-processing factor 19; PRP19; PRP19/PSO4; PRPF19; PSO4; senescence evasion factor; SNEV; UBOX4.

Gene ID

27339

Swiss Prot

Q9UMS4

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PRPF19

Clonality

Recombinant

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human PRPF19

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

27339

Isotype

IgG

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