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NLRP3 Recombinant Antibody

Product Specifications

Background

Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis.

Synonyms

FCU; MWS; FCAS; Cias1; Mmig1; NLRP3; Pypaf1; AII/AVP; AGTAVPRL; Cryopyrin.

Gene ID

114548

Swiss Prot

Q96P20

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

NLRP3

Clonality

Recombinant

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human NLRP3

Applications

ICC/IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

ICC/IF (1:50-100)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Prediction Reactivity

Mouse, Rat

Gene ID URL

114548

Isotype

IgG

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