NLRP3 Recombinant Antibody
Product Specifications
Background
Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis.
Synonyms
FCU; MWS; FCAS; Cias1; Mmig1; NLRP3; Pypaf1; AII/AVP; AGTAVPRL; Cryopyrin.
Gene ID
114548
Swiss Prot
Q96P20
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
NLRP3
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human NLRP3
Applications
ICC/IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse, Rat
Gene ID URL
114548
Isotype
IgG
Curated Selection
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