APC Recombinant Antibody, PE Conjugated
Product Specifications
Background
Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF) -induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Associates with both microtubules and actin filaments, components of the cytoskeleton.
Synonyms
APC; APC protein; Adenomatous polyposis coli protein; DP2.5; mAPC.
Gene ID
324
Swiss Prot
P25054
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
APC
Clonality
Recombinant
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human APC
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
324
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9321046-01 48 Well
Human Serine/threonine-protein phosphatase 5, PPP5C ELISA Kit
Ask
View Details 
MBS9321046-02 96 Well
Human Serine/threonine-protein phosphatase 5, PPP5C ELISA Kit
Ask
View Details MBS9321046-03 5x 96 Well
Human Serine/threonine-protein phosphatase 5, PPP5C ELISA Kit
Ask
View Details MBS9321046-04 10x 96 Well
Human Serine/threonine-protein phosphatase 5, PPP5C ELISA Kit
Ask
View Details 
207795-PE 100 µL
MKNK1 (MAP Kinase Interacting Serine/Threonine Kinase 1, MAP Kinase Interacting Kinase 1, MAP Kinase-Interacting serine/Threonine Kinase 1, OTTHUMP00000009674, MNK1) (PE)
Ask
View Details 