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HnRNP K Recombinant Antibody

Product Specifications

Background

Facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP K contains three unique structural motifs termed KH domains that bind poly (C) DNA and RNA sequences. Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis, transcriptional regulation, and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor.

Synonyms

65 kDa phosphoprotein; CSBP; TUNP; HNRNPK; HNRPK; DC-stretch binding protein; hnRNP-K.

Gene ID

3190

Swiss Prot

P61978

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

HnRNP K

Clonality

Recombinant

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human hnRNP K

Applications

WB, IHC-P, IHC-F, IP, IF, ICC/IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IP (1-2ug), IF (), ICC/IF (1:50-100)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

3190

Isotype

IgG

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