DAXX Recombinant Antibody, Cy3 Conjugated
Product Specifications
Background
Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby.
Synonyms
Death domain-associated protein 6; Daxx; hDaxx; Fas death domain-associated protein; ETS1-associated protein 1; EAP1; DAXX; BING2; DAP6.
Gene ID
1616
Swiss Prot
Q9UER7
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
DAXX
Clonality
Recombinant
Conjugation
Cy3
Source
KLH conjugated synthetic peptide derived from human DAXX
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1616
Isotype
IgG
Curated Selection
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