Acetyl CoA carboxylase Recombinant Antibody, HRP Conjugated
Product Specifications
Background
ACC1 a subunit of acetyl-CoA carboxylase (ACC), a multifunctional enzyme system. Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Acetyl-CoA carboxylase (ACC) catalyzes the pivotal step of the fatty acid synthesis pathway. The 265 kDa ACCŚÁ (ACC1) is the predominant isoform found in liver, adipocytes, and mammary gland, while the 280 kDa ACCŚÂ (ACC2) is the major isoform in skeletal muscle and heart.
Synonyms
ACAC; ACACA; ACACB; ACC; ACC-alpha; ACC1; ACC2; ACCA; ACCB; Acetyl-CoA carboxylase 1; Biotin carboxylase.
Gene ID
32
Swiss Prot
O00763
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Acetyl CoA carboxylase
Clonality
Recombinant
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human Acetyl CoA carboxylase
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1 mg/ml
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
32
Isotype
IgG
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