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Lamin B Receptor Recombinant Antibody, APC Conjugated

Product Specifications

Background

Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation .Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation.Anchors the lamina and the heterochromatin to the inner nuclear membrane.

Synonyms

PHA; LMN2R; TDRD18; DHCR14B; LBR.

Gene ID

3930

Swiss Prot

Q14739

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Target

Lamin B Receptor

Clonality

Recombinant

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human Lamin B Receptor

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3930

Isotype

IgG

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