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PP2A alpha/beta Recombinant Antibody, HRP Conjugated

Product Specifications

Background

Protein phosphatase type 2A (PP2A) is an essential protein serine/threonine phosphatase that is conserved in all eukaryotes. PP2A is a key enzyme within various signal transduction pathways as it regulates fundamental cellular activities such as DNA replication, transcription, translation, metabolism, cell cycle progression, cell division, apoptosis and development. The core enzyme consists of catalytic C and regulatory A (or PR65) subunits, with each subunit represented by ŚÁ and ŚÂ isoforms.

Synonyms

PP2A alpha; PP2A beta; Replication protein C; PPP2CA; PPP2CB.

Gene ID

5516

Swiss Prot

P62714, P67775

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PP2A alpha/beta

Clonality

Recombinant

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human PP2A alpha

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5516

Isotype

IgG

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