PIM1 Recombinant Antibody, PE-Cy7 Conjugated
Product Specifications
Background
Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5, FOXO3) .
Synonyms
Oncogene PIM1; PIM; pim-1 kinase 44 kDa isoform; pim-1 oncogene; pim-1 oncogene (proviral integration site 1) ; PIM1.
Gene ID
5292
Swiss Prot
P11309
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
PIM1
Clonality
Recombinant
Conjugation
PE-Cy7
Source
KLH conjugated synthetic peptide derived from human PIM1
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5292
Isotype
IgG
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