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MGluR5 Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.

Synonyms

GPRC1E; GRM5; Metabotropic glutamate receptor 5 precursor; MGLUR5; MGR5.

Gene ID

2915

Swiss Prot

P41594

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse, Rat

Target

MGluR5

Clonality

Recombinant

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human mGluR5

Applications

IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Product Datasheet

https://www.biossantibodies.com/datasheets/bsm-61218R-Biotin

Gene ID URL

2915

Isotype

IgG

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