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MGluR5 Recombinant Antibody, Cy3 Conjugated

Product Specifications

Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.

Synonyms

GPRC1E; GRM5; Metabotropic glutamate receptor 5 precursor; MGLUR5; MGR5.

Gene ID

2915

Swiss Prot

P41594

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse, Rat

Target

MGluR5

Clonality

Recombinant

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human mGluR5

Applications

IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

Lot dependent

Dilution

IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2915

Isotype

IgG

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