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LIN28B Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c. Binds primary let-7 transcripts (pri-let-7), including pri-let-7g and pri-let-7a-1, and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their processing into mature miRNA.

Synonyms

CSDD2; FLJ16517; LIN28B; Protein lin-28 homolog B.

Gene ID

389421

Swiss Prot

Q6ZN17

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

LIN28B

Clonality

Recombinant

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Lin 28B

Applications

WB, IP

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IP (1-2ug)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

389421

Isotype

IgG

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