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RPS3 Recombinant Antibody

Product Specifications

Background

Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) . Has also been shown to bind with similar affinity to intact and damaged DNA.

Synonyms

RPS3; 40S ribosomal protein S3.

Gene ID

6188

Swiss Prot

P23396

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

RPS3

Clonality

Recombinant

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human RPS3

Applications

IHC-P, IHC-F, IF, ICC/IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

IHC-P (1:200-400), IHC-F (1:100-500), IF (), ICC/IF (1:50-100)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

6188

Isotype

IgG

Curated Selection

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