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Phospho-Histone H1.4 (Thr17) Recombinant Antibody, APC Conjugated

Product Specifications

Background

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.

Synonyms

Histone H1b; Histone H1s-4.

Gene ID

3008

Swiss Prot

P10412

Modification Site

Thr17

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Histone H1.4

Clonality

Recombinant

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human Histone H1.4 around the phosphorylation site of T17

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3008

Isotype

IgG

Curated Selection

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