Phospho-Histone H1.4 (Thr17) Recombinant Antibody, HRP Conjugated
Product Specifications
Background
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
Synonyms
Histone H1b; Histone H1s-4.
Gene ID
3008
Swiss Prot
P10412
Modification Site
Thr17
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Histone H1.4
Clonality
Recombinant
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human Histone H1.4 around the phosphorylation site of T17
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3008
Isotype
IgG
Curated Selection
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