Phospho-Histone H2B.1 (Thr129) Recombinant Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
HTB2; Htb2p; HTB1; Htb1p; Histone H2B.1; Histone H2B.2; SPT12.
Gene ID
851810
Swiss Prot
P02293
Modification Site
Thr129
Host
Rabbit
Cross Reactivity
Human, Yeast
Target
Histone H2B.1
Clonality
Recombinant
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from yeast Histone H2B.1 around the phosphorylation site of T129
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
851810
Isotype
IgG
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