Phospho-Histone H2B.1 (Thr129) Recombinant Antibody, FITC Conjugated
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
HTB2; Htb2p; HTB1; Htb1p; Histone H2B.1; Histone H2B.2; SPT12.
Gene ID
851810
Swiss Prot
P02293
Modification Site
Thr129
Host
Rabbit
Cross Reactivity
Human, Yeast
Target
Histone H2B.1
Clonality
Recombinant
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from yeast Histone H2B.1 around the phosphorylation site of T129
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
851810
Isotype
IgG
Curated Selection
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