Phospho-Histone H2B.1 (Thr129) Recombinant Antibody
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
HTB2; Htb2p; HTB1; Htb1p; Histone H2B.1; Histone H2B.2; SPT12.
Gene ID
851810
Swiss Prot
P02293
Modification Site
Thr129
Host
Rabbit
Cross Reactivity
Human, Yeast
Target
Histone H2B.1
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from yeast Histone H2B.1 around the phosphorylation site of T129
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Phosphorylation
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
851810
Isotype
IgG
Curated Selection
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