Phospho-Histone H2A (Ser129) Recombinant Antibody, APC Conjugated
Product Specifications
Background
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Synonyms
FLJ92027; H2A histone family, member C; H2A.1; H2A/c; H2A1; H2AFC; H2AFD; H2AFI; H2AFN; H2AFP; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM.
Gene ID
852283
Swiss Prot
P04912
Modification Site
Ser129
Host
Rabbit
Cross Reactivity
Human, Yeast
Target
Histone H2A
Clonality
Recombinant
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from yeast Histone H2A around the phosphorylation site of S129
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
852283
Isotype
IgG
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