Phospho-Histone H2A (Ser129) Recombinant Antibody, APC Conjugated

Product Specifications

Background

Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Synonyms

FLJ92027; H2A histone family, member C; H2A.1; H2A/c; H2A1; H2AFC; H2AFD; H2AFI; H2AFN; H2AFP; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM.

Gene ID

852283

Swiss Prot

P04912

Modification Site

Ser129

Host

Rabbit

Cross Reactivity

Human, Yeast

Target

Histone H2A

Clonality

Recombinant

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from yeast Histone H2A around the phosphorylation site of S129

Applications

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

852283

Isotype

IgG

Curated Selection

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