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PTPN6 Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.

Synonyms

70Z-SHP; EC 3.1.3.48; HCP; HCPH; PTN6; PTP-1C; PTP1C; PTPN6; SH-PTP1; SHP1.

Gene ID

5777

Swiss Prot

P29350

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

PTPN6

Clonality

Recombinant

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human SHP1

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Prediction Reactivity

Rat

Gene ID URL

5777

Isotype

IgG

Curated Selection

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