PTPN6 Recombinant Antibody, PE Conjugated
Product Specifications
Background
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Synonyms
70Z-SHP; EC 3.1.3.48; HCP; HCPH; PTN6; PTP-1C; PTP1C; PTPN6; SH-PTP1; SHP1.
Gene ID
5777
Swiss Prot
P29350
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
PTPN6
Clonality
Recombinant
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human SHP1
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Rat
Gene ID URL
5777
Isotype
IgG
Curated Selection
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