Cathepsin D Recombinant Antibody, HRP Conjugated
Product Specifications
Background
Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Synonyms
CATD; Cathepsin D; Cathepsin D heavy chain; Cathepsin D light chain; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; CTSD; lysosomal aspartyl peptidase; lysosomal aspartyl protease; MGC2311.
Gene ID
1509
Swiss Prot
P07339
Cellular Locus
Cytoplasm, Secreted
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Cathepsin D
Clonality
Recombinant
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human Cathepsin D
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1509
Isotype
IgG
Curated Selection
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