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P57 Kip2/Cdkn1c Recombinant Antibody, HRP Conjugated

Product Specifications

Background

Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.

Synonyms

BWCR; BWS; KIP2; WBS; p57; p57 Kip2; WBS ; CDKN1C; Cyclin dependent kinase inhibitor 1C.

Gene ID

1028

Swiss Prot

P49918

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

P57 Kip2/Cdkn1c

Clonality

Recombinant

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human p57 Kip2

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1028

Isotype

IgG

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