CD146 Recombinant Antibody
Product Specifications
Background
CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development.
Synonyms
A32 antigen; CD 146; CD146; CD146 antigen; Cell surface glycoprotein P1H12; Gicerin; MCAM; Melanoma adhesion molecule; Melanoma associated antigen A32.
Gene ID
4162
Swiss Prot
P43121
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
CD146
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human MCAM
Applications
WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IP (1-2ug), IF (), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
4162
Isotype
IgG
Curated Selection
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