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PMEL Recombinant Antibody, APC Conjugated

Product Specifications

Background

Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.

Synonyms

PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV.

Gene ID

6490

Swiss Prot

P40967

Cellular Locus

Extracellular, Secreted

Host

Rabbit

Cross Reactivity

Human

Target

PMEL

Clonality

Recombinant

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human PMEL

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6490

Isotype

IgG

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