Phospho-CREB-1 (Ser133) Recombinant Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation.
Synonyms
CAMP responsive element binding protein 1; CREB1; CREB-1.
Gene ID
1385
Swiss Prot
P16220
Modification Site
Ser131
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
CREB
Clonality
Recombinant
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human CREB1 around the phosphorylation site of S133
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1385
Isotype
IgG
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