Phospho-CREB-1 (Ser133) Recombinant Antibody, HRP Conjugated
Product Specifications
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation.
Synonyms
CAMP responsive element binding protein 1; CREB1; CREB-1.
Gene ID
1385
Swiss Prot
P16220
Modification Site
Ser131
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
CREB
Clonality
Recombinant
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human CREB1 around the phosphorylation site of S133
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1385
Isotype
IgG
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