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Phospho-CREB-1 (Ser133) Recombinant Antibody, Cy3 Conjugated

Product Specifications

Background

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation.

Synonyms

CAMP responsive element binding protein 1; CREB1; CREB-1.

Gene ID

1385

Swiss Prot

P16220

Modification Site

Ser131

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

CREB

Clonality

Recombinant

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human CREB1 around the phosphorylation site of S133

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1385

Isotype

IgG

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