RNF20 Recombinant Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1) . H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively) . It thereby plays a central role inb histone code and gene regulation.

Synonyms

BRE1-A; hBRE1; RING finger protein 20; E3 ubiquitin-protein ligase BRE1A; RNF20.

Gene ID

56254

Swiss Prot

Q5VTR2

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

RNF20

Clonality

Recombinant

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human RNF20

Applications

WB, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

56254

Isotype

IgG

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