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RNF20 Recombinant Antibody, HRP Conjugated

Product Specifications

Background

Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1) . H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively) . It thereby plays a central role inb histone code and gene regulation.

Synonyms

BRE1-A; hBRE1; RING finger protein 20; E3 ubiquitin-protein ligase BRE1A; RNF20.

Gene ID

56254

Swiss Prot

Q5VTR2

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

RNF20

Clonality

Recombinant

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human RNF20

Applications

WB

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

56254

Isotype

IgG

Curated Selection

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