APPL1 Recombinant Antibody
Product Specifications
Background
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
Synonyms
Adapter protein containing PH domain; Adaptor Protein Containing pH Domain; Adaptor protein containing pH domain PTB domain and leucine zipper motif 1; Adaptor protein containing pH domain PTB domain and leucine zipper motif; AKT2 INTERACTOR; APPL 1; APPL1; DCC interacting protein 13 alpha; DCC-interacting protein 13-alpha; DIP 13 alpha; DIP13 alpha; Dip13-alpha; DIP13alpha; DP13A_HUMAN; KIAA1428; PTB domain and leucine zipper motif 1; PTB Domain and Leucine Zipper Motif; Signaling adaptor protein DIP13alpha.
Gene ID
26060
Swiss Prot
Q9UKG1
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
APPL1
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human APPL1
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
26060
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
042599-AP 200 µL
TAPBPL, NT (TAPBPL, Tapasin-related protein, TAP-binding protein-like, TAP-binding protein-related protein, Tapasin-like) (AP) discontinued
Ask
View Details