WT1 Recombinant Antibody, Biotin Conjugated
Product Specifications
Background
Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
Synonyms
WT1_HUMAN; Wilms tumor protein; WT33; WT1 transcription factor; GUD; AWT1; WAGR; WT-1; WT33; NPHS4; WIT-2
Gene ID
7490
Swiss Prot
P19544
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
WT1
Clonality
Recombinant
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human WT1
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1mg/ml
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
7490
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
249970-ML550 100 µL
PECAM1 (Platelet/Endothelial Cell Adhesion Molecule, CD31, PECAM-1) (MaxLight 550)
Ask
View Details 
GTR15279378 1 Vial
Lentiviral mouse Pcp4l1 shRNA (UAS) - Lentiviral mouse Pcp4l1 shRNA (UAS) (100)
Ask
View Details 
32-5067-10 10 µg
Recombinant Human Transforming Growth Factor Beta Receptor Associated Protein 1
Ask
View Details 341615-01 100 µL
HSD17B11 (HSD17B11, DHRS8, PAN1B, Estradiol 17-beta-dehydrogenase 11, 17-beta-hydroxysteroid dehydrogenase 11, 17-beta-hydroxysteroid dehydrogenase XI, Cutaneous T-cell lymphoma-associated antigen HD-CL-03, Dehydrogenase/reductase SDR family member 8, Retinal short-chain dehydrogenase/reductase 2) discontinued
Ask
View Details 341615-02 200 µL
HSD17B11 (HSD17B11, DHRS8, PAN1B, Estradiol 17-beta-dehydrogenase 11, 17-beta-hydroxysteroid dehydrogenase 11, 17-beta-hydroxysteroid dehydrogenase XI, Cutaneous T-cell lymphoma-associated antigen HD-CL-03, Dehydrogenase/reductase SDR family member 8, Retinal short-chain dehydrogenase/reductase 2) discontinued
Ask
View Details