Catalase Recombinant Antibody
Product Specifications
Background
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]
Synonyms
Cas1; CAT; Cs1; MGC138422; MGC138424; CATA_HUMAN.
Gene ID
847
Swiss Prot
P04040
Cellular Locus
Cytoplasm
Host
Mouse
Cross Reactivity
Human
Target
Catalase
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Catalase
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein G.
Concentration
1mg/ml
Dilution
WB (WB (1:500-2000) ), IHC-P (IHC-P (1:1000) ), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse, Rat
Gene ID URL
847
Isotype
IgG1/Kappa
Curated Selection
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