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URI1 Recombinant Antibody

Product Specifications

Background

This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22. [provided by RefSeq, Nov 2011]

Synonyms

C19orf2; Chromosome 19 open reading frame 2; NNX3; PPP1R19; Protein NNX3; Protein phosphatase 1 regulatory subunit 19; RMP_HUMAN; RNA polymerase II subunit 5 mediating protein; RNA polymerase II subunit 5-mediating protein; RPB5 mediating protein; RPB5-mediating protein; Unconventional prefoldin RPB5 interactor 1; Unconventional prefoldin RPB5 interactor; URI; URI1, prefoldin-like chaperone.

Gene ID

8725

Swiss Prot

O94763

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

URI1

Clonality

Recombinant

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human STMN1

Applications

WB, IHC-P, IHC-F, IF, ICC/IF

Purification

Purified by Protein A.

Concentration

1mg/ml

Dilution

WB (WB=1:500-2000), IHC-P (IHC-P=1:200-500), IHC-F (ICC=1:50), IF (IF=1:50-100), ICC/IF (1:50-100)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

8725

Isotype

IgG

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