Keratin 4 Recombinant Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Synonyms
CK 4; CK4; CYK 4; CK-4; CYK4; Cytokeratin4; Cytokeratin-4; FLJ31692; K4; Keratin 4; Keratin-4; Keratin type II cytoskeletal 4; Keratin4; KRT 4; KRT4; K2C4_HUMAN; Keratin, type II cytoskeletal 4; K4; Type-II keratin Kb4.
Gene ID
3851
Swiss Prot
P19013
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Keratin 4
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Keratin 4
Applications
IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
Lot Dependent
Dilution
IHC-P (IHC-P (1:1000-5000) ), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
3851
Isotype
IgG
Curated Selection
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